Calcium Hydroxyapatite (CaHA) Services
BOC Sciences provides a wide range of services for calcium hydroxylapatite (CaHA) production and application, primarily used in aesthetic and therapeutic treatments. Our CaHA services include the synthesis, purification, and formulation of high-quality, biocompatible products for dermal filler applications. We leverage advanced biotechnological techniques and rigorous quality assurance procedures to deliver CaHA products with excellent stability, biocompatibility, and safety profiles. Whether for enhancing facial volume, improving skin elasticity, or other medical uses, BOC Sciences’ CaHA services are designed to meet the highest standards in the cosmetic and pharmaceutical industries, offering flexible and scalable solutions for a variety of client needs.
What is Calcium Hydroxylapatite (CaHA)?
Calcium hydroxylapatite is a biodegradable mineral compound with biocompatibility that consists of calcium and phosphate elements and shares structural similarities with natural minerals present in human bones and teeth. CaHA has become a fundamental material in both dermal filler formulations and regenerative medicine because of its exceptional safety profile and collagen production stimulation capabilities. CaHA particles injected into soft tissue produce an immediate volume enhancement and stimulate collagen production that supports ongoing natural tissue remodeling. CaHA delivers better longevity than hyaluronic acid-based fillers while providing improved lifting results and smoother skin texture through biostimulation. CaHA has expanded its utility beyond aesthetic uses to become an important scaffold material for bone regeneration and defect repair in orthopedic and dental practices as well as tissue engineering.
Outstanding Advantages of BOC Sciences’ CaHA Development
Customized R&D Process
We offer end-to-end customized services covering everything from CaHA synthesis to application. Our solutions are tailored to meet specific customer requirements, ensuring precision and efficiency at every stage.
Comprehensive Technical Support
With an experienced biochemical R&D team, we provide full-spectrum technical support — from CaHA synthesis and characterization to application — helping clients overcome technical challenges with confidence.
Efficient R&D Cycle
By optimizing workflows and leveraging advanced laboratory equipment, we significantly shorten the development timeline of CaHA-related projects, enabling rapid responses to customer needs.
Strict Quality Control
We implement a rigorous quality control system throughout CaHA synthesis and application, ensuring every product meets international standards and client specifications.
Seamless Transition from Lab to Industrial Scale
Beyond laboratory-scale R&D, we assist clients in achieving smooth transitions to industrial production, reducing the complexity and risks of scaling up CaHA manufacturing.
Flexible Project Management
Our flexible project management approach allows us to adjust timelines and strategies according to client goals, ensuring on-time delivery and expected outcomes.
Innovative Solutions
By integrating cutting-edge biochemical technologies with market insights, we provide innovative CaHA application solutions to help clients stand out in competitive markets.
Long-Term Partnership and Technical Support
We are committed to building long-term collaborations, offering continuous technical support and after-sales service to ensure lasting success in CaHA research and applications.
Comprehensive Calcium Hydroxyapatite Services by BOC Sciences
BOC Sciences offers a wide range of calcium hydroxyapatite (CaHA) products, including medical-grade CaHA for dermal fillers and bone repair, nano CaHA for advanced drug delivery systems, and microsphere CaHA for cosmetic and orthopedic applications. Our product portfolio also includes surface-modified CaHA, composite CaHA materials, and custom-formulated CaHA solutions, all designed to meet the specific requirements of diverse applications in both medical and aesthetic fields.
CaHA Microsphere Preparation
BOC Sciences specializes in the precise preparation of CaHA microspheres, offering controlled particle size, uniform morphology, and enhanced biocompatibility for diverse biomedical applications. Our advanced synthesis techniques ensure consistent quality and tailored properties, supporting both cosmetic and orthopedic product development. Through strict process control and customized formulations, we help clients obtain microspheres optimized for injectability, longevity, and functional performance in research settings.
CaHA Filler Formulation Services
BOC Sciences provides comprehensive CaHA filler formulation services designed to meet the unique requirements of aesthetic and regenerative medicine. Our services include customizing the ratio of CaHA microspheres to carriers, improving rheological properties, and enhancing skin-lifting effects. Whether for facial contouring or skin rejuvenation, we ensure precise formulation, safety, and stability, enabling high-quality, market-ready filler products for medical and cosmetic use.
CaHA Nanoparticle Development
BOC Sciences delivers expert CaHA nanoparticle development which prioritizes ultra-fine particle design to improve cellular uptake and drug delivery while maximizing bioactivity. Our customized synthesis methods provide exact control over particle size, crystallinity and surface properties which fulfill requirements for targeted therapies and regenerative medicine applications. Clients have the opportunity to research new applications from bone regeneration to sustained-release systems through this service.
CaHA Quality Control Testing
BOC Sciences provides a full suite of CaHA quality control testing services to ensure product safety, consistency, and regulatory compliance. Our testing covers microbiological, chemical, and physical parameters, including heavy metal detection, sterility, pH, stability, and biocompatibility. Using validated analytical methods, we help clients confirm the reliability and performance of CaHA-based products, supporting smooth market approval and batch release.
CaHA In Vitro and In Vivo Testing
BOC Sciences performs complete laboratory and animal testing procedures to determine the biological safety and functional performance of CaHA products. Our research examines cytotoxicity and tissue integration along with immune response and degradation behavior across multiple experimental settings. The rigorous testing protocols generate dependable data which supports product improvement and quality assurance thus guaranteeing CaHA materials remain safe and consistent for therapeutic and cosmetic use.
GMP-Compliant Production of CaHA for Biomedicine and Cosmetics
BOC Sciences delivers CaHA production services with advanced quality controls that satisfy the top material standards for biomedical, environmental, and industrial applications. We establish a thorough quality management system that includes raw material screening along with precise compositional control and particle size morphology consistency for non-injectable CaHA products even though GMP certification is usually not required. Every batch receives comprehensive testing to verify phase purity, chemical stability and biocompatibility which guarantees dependable functionality in bone repair systems as well as heavy metal ion adsorption and catalytic applications.
Analytical Testing Services for CaHA
BOC Sciences delivers full-scale analytical testing to monitor CaHA safety standards alongside its purity and operational effectiveness in both medical and cosmetic uses. Our testing portfolio includes essential evaluations of physical elements along with chemical and biological parameters to support raw material verification while optimizing processes and validating products. By using sophisticated analytical equipment along with strict quality control measures we supply precise and repeatable information to meet quality standards and support risk analysis. We conduct thorough biocompatibility evaluations while also performing stability and degradation testing that matches CaHA's specific applications beyond our routine quality control tests. Our integrated testing services enable clients to achieve formulation reliability as well as patient safety while guaranteeing smooth market entry.
Product Quality and Safety Testing
Microbiological Testing Chemical Hygiene Inspection pH Measurement Stability Testing Toxicological Testing Safety Assessment Toxicological Evaluation
Biological Performance and Functional Evaluation
Biocompatibility Testing Biocompatibility Evaluation Long-Term Biocompatibility Study Degradation Behavior Study Drug Release Profile Testing Bone Regeneration Capability Assessment Histological Evaluation Imaging Analysis
What are the Applications of CaHA?
Facial Fillers
CaHA is widely used as a dermal filler for soft tissue augmentation, especially for correcting moderate to severe nasolabial folds, facial wrinkles, and volume loss. It stimulates collagen and elastin production, restores skin elasticity, and enhances facial contours, delivering natural-looking and long-lasting rejuvenation.
Skin Tightening and Anti-Aging
CaHA treatment is commonly used to tighten skin in regions such as the neck, shoulders, and hips. The diluted or hyper-diluted versions of this substance stimulate neocollagenesis and skin remodeling which reduces fine lines, wrinkles, and sagging.
Orthopedic and Dental Applications
Due to its excellent biocompatibility and osteoconductive properties, CaHA is widely applied in orthopedics and dentistry. It serves as a bone graft substitute in skeletal repair, dental implant coatings, and craniofacial reconstruction, supporting bone growth, integration.
Heavy Metal Ion Immobilization
CaHA exhibits strong adsorption and ion-exchange capabilities, making it highly effective in immobilizing heavy metal ions such as lead, cadmium, and zinc in wastewater. It is commonly used in environmental remediation to reduce metal ion mobility, enhancing water purification and ecosystem safety.
Biomedical Adsorbent
Thanks to its high surface area and chemical stability, CaHA serves as an efficient adsorbent for biological molecules. It is widely employed for the separation and purification of proteins, enzymes, and bioactive substances in biopharmaceutical research and production processes.
Catalysts and Sensors
CaHA plays a valuable role in catalytic and sensing technologies. It is used as a solid support for catalysts, ion conductors, gas sensors, and temperature or humidity sensors. Its stability and unique surface properties improve detection sensitivity and reaction efficiency in various industrial applications.
Aesthetic Medicine
CaHA is often combined with other fillers like hyaluronic acid to achieve enhanced and longer-lasting cosmetic results. The synergy offers superior skin volumization, wrinkle reduction, and biostimulation while lowering the risk of adverse effects and optimizing the aesthetic outcome.
Animal Model Surgery
CaHA is also applied in animal model surgeries as a scaffold for studying soft tissue repair and regeneration. It provides a biocompatible, stable matrix to simulate human tissue healing, supporting preclinical research in reconstructive medicine and biomaterial development.
FAQs
What is Calcium Hydroxyapatite and what makes it so popular in medical applications?
CaHA (Calcium Hydroxyapatite) is a biocompatible material used for dermal fillers and bone regeneration, offering natural integration, longevity, and excellent mechanical and biological properties.
What are the main applications of CaHA materials?
CaHA is used in aesthetic fillers, orthopedic implants, bone defect repair, drug delivery systems, and regenerative medicine due to its biocompatibility, stability, and customizable particle design.
How does CaHA compare to other filler materials?
CaHA offers longer-lasting results, superior tissue integration, and a natural stimulation of collagen production, making it a preferred choice over hyaluronic acid in both cosmetic and medical fields.
What types of CaHA materials can BOC Sciences provide?
BOC Sciences offers CaHA microspheres, nanoparticles, and fillers with customizable particle size, morphology, and surface properties, meeting the demands of both cosmetic and orthopedic product development.
Do you offer biological performance testing for CaHA materials?
Yes, we provide in vitro and in vivotesting to assess cytotoxicity, tissue integration, immune response, and degradation, ensuring safe and effective use in cosmetic and medical applications.