PDRN Gel Development
BOC Sciences has extensive experience in the development of PDRN gels, committed to providing high-quality PDRN gel products and customized development services to global clients. We have advanced equipment and technology, enabling us to offer comprehensive services from PDRN solution preparation to gel formulation optimization. Our goal is to meet the needs of customers in various fields, including pharmaceuticals, skincare, and regenerative medicine, by providing efficient, stable, and GMP-compliant PDRN gel solutions through innovative technology and precise process design.
What is PDRN?
Polydeoxyribonucleotide (PDRN) originates from natural deoxyribonucleic acid (DNA) through the hydrolysis process of DNA sourced from salmon sperm. The medical and cosmetic industries extensively utilize PDRN because its distinctive molecular structure stimulates cell growth and regeneration. The primary advantages of PDRN are its abilities to repair skin tissue while simultaneously enhancing tissue regeneration and improving blood circulation. Generally, PDRN speeds up skin and soft tissue healing by triggering growth factor secretion during recovery from trauma or surgery. In addition, PDRN demonstrates anti-inflammatory properties that provide relief for inflammatory skin disorders such as eczema and psoriasis. Currently, PDRN receives extensive usage in skincare and tissue engineering fields because it possesses strong regenerative capabilities and displays outstanding biocompatibility.
Advantages of BOC Sciences in PDRN Gel Development
Professional PDRN Research Team
Our team consists of experienced scientists and R&D personnel focused on the development and innovation of PDRN-related technologies.
Advanced Production Technology
We utilize efficient PDRN extraction, purification, and preparation processes to ensure product quality stability and high activity.
Customized Formulation Development
We offer personalized PDRN gel formulation design to meet various application needs, including anti-aging and wound repair.
Strict Quality Control
All production processes comply with GMP standards, using advanced analytical instruments to ensure the safety and stability of PDRN gels.
Comprehensive Industry Chain Support
From raw material procurement, formulation optimization to large-scale production, we provide one-stop solutions for our clients.
Innovative Skin Penetration Technology
Combining advanced delivery systems, we enhance PDRN absorption in the skin to improve its efficacy.
Global Market Supply Capability
With internationally certified production facilities, we can meet the global demand for high-quality PDRN gels.
Comprehensive Regulatory Compliance Support
We provide product declaration and compliance guidance to help clients smoothly enter their target markets.
PDRN Gel Development Services by BOC Sciences
BOC Sciences offers comprehensive PDRN gel development services aimed at ensuring that clients receive efficient, stable, and market-ready products through professional technology and precise process design. From PDRN solution preparation to the final gel filling, we provide accurate support for every step. Whether in skincare, anti-aging, or wound repair, our gel development services provide stable and effective solutions. Our development services include, but are not limited to, the following key steps:
PDRN Solution Preparation
We use advanced extraction technology to obtain high-quality PDRN from natural sources (such as fish sperm) and employ precise purification techniques to remove impurities, ensuring high activity and stability of the final product.
Gel Matrix Preparation
Based on customer requirements, we select appropriate gel matrix materials, including various natural and synthetic types, such as hyaluronic acid, carbomer, and xanthan gum, to ensure the texture, stability, and comfort of the final gel.
PDRN Gel Preparation
Using precise mixing techniques, we fully blend the PDRN solution with the gel matrix at appropriate temperatures and conditions to ensure uniform distribution of PDRN components and achieve the desired product efficacy.
Sterilization and Filling
To ensure the safety and stability of PDRN gel, we use sterile processes for sterilization and precise filling, ensuring the product remains uncontaminated during transport and use.
PDRN Gel Formulation Optimization by BOC Sciences
In the development of PDRN gel, BOC Sciences understands the importance of formulation optimization for product efficacy, stability, and user experience. With years of technological accumulation and R&D experience, we strive to provide comprehensive PDRN gel formulation optimization services, ensuring that every batch of products achieves the best results. Our formulation optimization services cover the following key areas, aimed at improving product efficacy, stability, skin penetration, and market competitiveness:
PDRN Concentration Optimization
Lower concentrations of PDRN (e.g., 0.1%) offer good effects for skin repair, while higher concentrations (e.g., 2%) may improve cell proliferation and tissue repair efficiency.
Thickener and Matrix Optimization
According to market requirements, appropriate thickeners and matrices are selected to improve the gel's viscosity and rheological properties, achieving the desired application effect.
Combination of Active Ingredients
In addition to PDRN, we combine moisturizing and antioxidant ingredients, such as glycerin, sorbitol, propylene glycol, and vitamin C, to enhance the comprehensive efficacy of the gel.
Preservative System Optimization
We optimize the preservative system according to the formulation needs, using milder, natural preservative ingredients to ensure product stability and safety during long-term storage.
Preparation Process Optimization
We employ low-temperature preparation techniques to prevent PDRN degradation at high temperatures, as well as sterile technologies such as terminal filtration, aseptic filling, and irradiation sterilization to ensure microbial safety of the finished product.
Skin Penetration Optimization
To enhance PDRN's skin penetration, penetration enhancers, nanoparticles, or liposome carriers (such as nano micelles or solid lipid nanoparticles) are used to effectively encapsulate PDRN.
Dosage Form Optimization
According to client needs, we develop PDRN gels for different dosage forms, such as sprays, patches, or roll-ons, to improve user convenience and comfort.
Efficacy Optimization
Based on customer requirements and product goals, we optimize the efficacy by adjusting PDRN concentration, usage frequency, and application sites to ensure the best repair effects without waste.
GMP Manufacturing Capability for PDRN Gels
BOC Sciences has advanced GMP-grade manufacturing facilities and a rigorous quality management system, enabling efficient production of high-quality PDRN gel that complies with international regulatory requirements. Our production workshops are designed according to cGMP standards and are equipped with sterile production lines, precisio n mixing systems, and efficient sterilization equipment to ensure the purity, stability, and safety of PDRN gel. During the manufacturing process, we employ automated control systems for precise formulation mixing, ensuring even distribution of PDRN in the gel, enhancing the product's bioactivity and transdermal absorption. We also have high-efficiency filtration and sterilization systems in place to effectively remove microorganisms and endotoxins, ensuring the sterility of the final product. BOC Sciences possesses complete capabilities for small-scale, pilot-scale, and large-scale production, capable of meeting the diverse production needs of our clients. Our GMP facilities are not only used for commercial batch production but also support product development during clinical research stages, aiding in the rapid market introduction of PDRN gel products.
Quality Testing Services for PDRN Gels
BOC Sciences is committed to providing high-quality PDRN gel products, ensuring their stability, safety, and efficacy in every batch. To achieve this goal, we have established a comprehensive quality testing service system that covers all stages, from raw materials to finished products, with strict monitoring of product quality. Our quality testing services meet industry standards and incorporate advanced analytical technologies to ensure that each product at every stage meets customer requirements and is adaptable to various market applications. The following are the main quality testing services provided by BOC Sciences during the PDRN gel development process:
Testing Platforms
High-Performance Liquid Chromatography (HPLC) Gel Permeation Chromatography (GPC) UV-Visible Spectrophotometer (UV-Vis) Rheometer Differential Scanning Calorimeter (DSC) Fourier Transform Infrared Spectroscopy (FTIR) Dynamic Light Scattering (DLS)
Testing Items
PDRN Content Analysis Molecular Weight Distribution Testing Stability Testing pH Value Testing Microbial Limit Testing Appearance and Sensory Evaluation Skin Permeability Testing
Applications of PDRN Gel in Skin Repair and Regeneration
PDRN, with its unique bioactivity, can promote cell proliferation and angiogenesis, significantly enhancing skin repair capabilities. Its main mechanism of action is activating A2A adenosine receptors, increasing the activity of fibroblasts, and accelerating collagen and elastin synthesis, thus improving skin elasticity, reducing wrinkles, and strengthening the skin barrier function. In the field of medical aesthetics, PDRN gel is widely used in anti-aging, acne scar repair, pigmentation improvement, and post-surgical skin repair. Additionally, due to its powerful tissue repair capabilities, PDRN also plays an important role in wound care, chronic wound healing, and joint and soft tissue repair.
Anti-Aging for Skin
PDRN gel promotes collagen and elastin synthesis, reduces fine lines and wrinkles, and enhances skin elasticity, making the skin firmer and more youthful.
Post-Surgical Repair
Used for skin repair after medical treatments like laser or microneedling, accelerating wound healing, reducing redness and inflammation, and lowering the risk of pigmentation.
Acne Scar Repair
PDRN promotes cell regeneration, improves acne scars, smoothens the skin, and reduces pigmentation and erythema left by acne.
Chronic Wound Healing
Suitable for chronic wounds such as diabetic foot ulcers and pressure sores, promoting angiogenesis, accelerating tissue repair, and improving wound healing rates.
Sensitive Skin Repair
Relieves skin sensitivity and inflammation, enhances the skin barrier function, improves the skin's tolerance to external stimuli, and reduces allergic reactions.
Pigmentation Improvement
By promoting cell renewal and vascular repair, PDRN helps even out skin tone, reducing melanin deposition and improving issues like melasma and sunspots.
Joint and Soft Tissue Repair
PDRN is used for soft tissue injuries, arthritis, and similar problems, promoting cartilage cell repair, alleviating pain, and enhancing movement function.
Scalp Health Improvement
Applied in scalp care to improve blood circulation, promote hair follicle repair, enhance hair growth, prevent hair loss, and increase hair density.
FAQs
Is PDRN salmon sperm?
PDRN (polydeoxyribonucleotide) is not merely salmon sperm but is derived from low molecular weight DNA fragments extracted from salmon sperm or reproductive cells. PDRN has strong cell repair and regeneration capabilities and is widely used in skincare, tissue repair, and anti-aging products. PDRN prepared via enzymatic hydrolysis technology promotes cell proliferation, improves blood circulation, and strengthens the skin barrier function, which is why it is commonly used in medical beauty treatments and reparative skincare products.
What is PDRN treatment for eyes?
PDRN eye treatment is a regenerative therapy based on PDRN ingredients, mainly used to improve aging, fine lines, dark circles, and puffiness around the eyes. PDRN stimulates fibroblast proliferation and collagen synthesis, improving skin elasticity and enhancing microcirculation, reducing pigmentation and puffiness. This therapy is typically administered via PDRN injection or PDRN gel, aiming to repair the eye skin barrier, making it firmer and hydrated, achieving a rejuvenating effect.
Is PDRN a filler?
PDRN is not a traditional skin filler (like hyaluronic acid fillers); it focuses more on cell repair and tissue regeneration. Fillers are typically used to add volume to the skin, while PDRN enhances skin quality by promoting cell regeneration, stimulating collagen synthesis, and improving microcirculation, making the skin firmer and more elastic. Therefore, PDRN is better suited as a biological regeneration therapy to improve skin condition in the long term, rather than for immediate volumizing or shaping.