Aesthetic Medicine
With strong formulation development capabilities and an advanced technology platform, BOC Sciences provides one-stop customized services for the medical aesthetics and cosmetics industries. These services range from ingredient screening, formulation optimization, and quality control to GMP manufacturing, helping global clients efficiently, compliantly, and safely transform R&D achievements into market-competitive products. Our interdisciplinary technical team integrates cutting-edge research in organic synthesis, biochemistry, materials science, and pharmaceutics to deliver personalized, high-quality formulation solutions for various topical formulations, injectable fillers, cosmetic peptides, and active ingredient delivery systems. Our clients include medical aesthetics institutions, skincare brands, biopharmaceutical companies, and premium cosmetics manufacturers. We are committed to advancing scientifically driven medical aesthetic products into clinical and commercial use.
Service Advantages of BOC Sciences in Medical Aesthetics
Customized Formulation Design Capability
BOC Sciences has a robust R&D team capable of tailoring functional formulations based on customer needs, optimizing stability, biocompatibility, and active ingredient release performance.
Advanced Raw Material Integration Platform
We integrate premium global raw material resources, covering peptides, proteins, polymers, and bioactive molecules, ensuring raw material quality and providing end-to-end technical services from screening to validation.
Interdisciplinary Technology Integration
Leveraging a multidisciplinary collaboration platform across chemistry, biology, and materials science, we continuously innovate in carrier development, transdermal technologies, and controlled release systems to meet diverse clinical and application demands.
Extensive Formulation Development Experience
BOC Sciences excels in various dosage form designs, such as gels, injections, microspheres, liposomes, emulsions, and lyophilized preparations, catering to differentiated product development needs in medical aesthetics and premium cosmetics.
High-Standard GMP Manufacturing System
The company is equipped with internationally compliant GMP facilities capable of pilot, scale-up, and commercial production, ensuring product safety, traceability, and consistency in line with regulatory standards.
Full-Process Project Management Mechanism
We offer end-to-end technical management services covering proof of concept, formulation screening, stability testing, and regulatory submission, helping clients advance projects efficiently and accelerate product launch timelines.
Formulation Development Service for Medical Aesthetics
In the field of medical aesthetics and cosmetics industries, BOC Sciences provides formulation design and technical optimization services for a variety of mainstream and emerging products, covering common injectable fillers, regenerative active ingredients, functional particles, and peptide systems. Our service scope includes but is not limited to the following product categories:
Botulinum Toxin Services
We participate in the formulation optimization and stabilization of Type A and B botulinum toxins, including prevention of protein aggregation, development of lyophilized dosage forms, and incorporation of sustained-release systems.
Calcium Hydroxyapatite (CaHA) Services
As a particulate filler, CaHA is widely used in facial contouring due to its dual functions of volume support and collagen stimulation. BOC Sciences provides services including CaHA particle embedding systems, dispersion stability improvement, and injectable formulation process development.
Collagen Services
Whether extracted from animal sources or produced via recombinant expression, we offer services for collagen purification, crosslinking, stabilization, and formulation, including lyophilized powders, injectables, and mask formulations for various applications.
Hyaluronic Acid (HA) Services
We have mature technologies for developing high-, medium-, and low-molecular-weight HA formulations, including crosslinked HA fillers, compound HA serums, and sustained-release carrier systems, supporting product development for moisturizing, repair, and shaping applications.
- Hyaluronic Acid Preparation
- Hyaluronic Acid Modification
- Hyaluronic Acid Microsphere Development
- Hyaluronic Acid Gel Development
- Hyaluronic Acid Nanogel Development
- Hyaluronic Acid Nanoparticle Development
- Hyaluronic Acid Scaffold Development
- Hyaluronic Acid Filler Development
- Hyaluronic Acid Formulation
- Hyaluronic Acid Quality Control Testing
- Hyaluronic Acid In Vitro and In Vivo Testing
Polydeoxyribonucleotide (PDRN) Services
BOC Sciences provides services including PDRN extraction and purification, concentration ratio optimization, and combination formulation design with other biofactors. These are widely applied in skin repair and tissue regeneration projects in medical aesthetics.
Polynucleotides (PN) Services
We develop sustained-release systems, penetration-enhancing combination technologies, and cold chain stability formulations for PN ingredients, used in products targeting cell regeneration, anti-aging, and antioxidation, especially in injectable aesthetics and post-surgical repair.
Polymethyl Methacrylate (PMMA) Services
PMMA microspheres are commonly used in permanent fillers due to their high stability and long-term support. We assist in particle size control, surface modification, and injectable formulation development for PMMA microspheres.
Polylactic Acid (PLA) Services
BOC Sciences has extensive experience in sustained-release drug delivery systems based on PLA particles and microspheres, suitable for long-acting fillers that stimulate collagen regeneration. We also support the construction of compound systems combining PLA with HA or collagen.
Polycaprolactone (PCL) Services
We develop its applications in injectable fillers, implantable sustained-release systems, and combination drug delivery platforms, suitable for deep tissue filling, volume modification, and high-end personalized cosmetic procedures.
Agarose Services
We offer gel development services based on agarose as a matrix, suitable for transparent injectable fillers or physical encapsulation systems, with good biocompatibility and injectability.
Exosome Services
For exosomes derived from various sources (e.g., mesenchymal stem cells), we provide extraction and purification, active component protection, lyophilized formulation development, and skin delivery system construction to meet functional needs in anti-inflammation, anti-aging, whitening, and more.
Peptides Services
For peptides such as oligopeptide-1, copper peptides, and botulinum-like peptides, BOC Sciences offers integrated solutions including peptide synthesis, encapsulation, sustained-release system design, and transdermal enhancement, accelerating the commercialization of functional skincare products.
Medical Aesthetic Support Technology by BOC Sciences
BOC Sciences is committed to providing advanced technological support for the medical aesthetics industry, covering active ingredient development, delivery system design, formulation optimization, and quality control. With a strong foundation in chemical synthesis and bioengineering technologies, we create high-performance, stable solutions for medical aesthetic products that meet clinical and market demands, helping drive innovation and industry upgrades.
Functional Ingredient Screening and Active Ingredient Optimization
Medical aesthetic formulations require active ingredients with higher standards than traditional skincare products. These ingredients must have clear mechanisms, good biocompatibility, and clinical-grade stability. BOC Sciences offers the following services:
- Functional Peptide Screening and Synthesis: such as collagen-inducing peptides, anti-wrinkle hexapeptides, whitening peptides, and anti-inflammatory peptides.
- Plant Extract and Small Molecule Optimization: enhancing antioxidant capacity, skin permeability, and stability through chemical modifications.
- Molecular Derivatization Design: such as modifying hyaluronic acid, coenzyme Q10, and Vitamin C to improve water solubility and controlled release properties.
- Non-natural Amino Acid/Sugar Derivative Design: improving enzyme resistance and extending functional longevity.
Formulation System Design and Development
We offer a range of formulation development services tailored to different product needs, including but not limited to:
- Emulsion/Cream/Gel Formulations: optimizing emulsifying systems and moisturizing factors to ensure skin feel and active ingredient stability.
- Nanoemulsions and Liposomal Carriers: improving ingredient transdermal efficiency and targeting, commonly used in anti-aging and whitening products.
- Microsphere/Microcapsule Encapsulation Technology: protecting sensitive ingredients, controlling release, and improving long-term stability.
- Transdermal Patches and Needle-free Injection Formulations: integrating innovative drug delivery technologies such as microneedles and thermosensitive gels, suitable for medical aesthetic treatments.
- Anhydrous Systems and Solid Dispersions: designed for special needs, such as sensitive skin or high-temperature environments.
Delivery Systems and Permeation Enhancement Technology
Medical aesthetic products often require active ingredients to penetrate the skin barrier and reach the target layers. BOC Sciences provides advanced skin delivery system designs, including:
- Liposomes, nanovesicles, and solid lipid nanoparticles (SLN) technology.
- Polymeric carriers (e.g., PEG, PCL) for sustained-release systems.
- Iontophoresis and ultrasound-based delivery formula compatibility development.
- Skin permeability enhancer screening and combination optimization.
- Biodegradable carrier systems for injectable products.
Stability Research and Quality Control Systems
The efficacy of cosmetics and medical aesthetic products largely depends on their stability. We conduct stability assessments following pharmaceutical-grade quality standards:
- Accelerated aging tests.
- Light and oxidation stability tests.
- Metal ion interference tests.
- Microbial load and preservative system validation.
- Monitoring physicochemical properties such as particle size, zeta potential, pH, viscosity.
GMP Manufacturing Capabilities and Facility Assurance
BOC Sciences operates GMP-compliant production workshops with full-scale manufacturing capabilities, from laboratory-scale trials to commercial production. Our facilities are equipped with advanced reaction systems, sterile filling lines, lyophilization systems, emulsification equipment, and high-precision filtration and purification systems, meeting the preparation requirements for various dosage forms (e.g., injectables, gels, microspheres, emulsions). The production environment is rigorously controlled according to ISO cleanroom standards, supporting sterile processing of high-potency ingredients and sensitive bioproducts. We offer one-stop GMP manufacturing services, including formulation verification, process transfer, release testing, and complete batch record systems, ensuring the quality, safety, regulatory compliance, and market efficiency of medical aesthetic and cosmetic products.
Multi-dimensional Quality Testing Service Platform
In the process of developing medical aesthetic and cosmetic formulations, precise quality testing is crucial for ensuring product safety, stability, and efficacy. BOC Sciences has established a systematic and standardized quality testing service platform, covering raw material identification, ingredient analysis, stability evaluation, particle contamination monitoring, and biocompatibility assessment. With advanced testing equipment and rigorous analytical methods, we provide reliable data support to accelerate the compliance process from product development to registration, enhancing the overall product quality assurance system.
Molecular weight distribution Viscosity and rheological properties analysis Particle size and zeta potential Appearance, color, pH, specific gravity testing Injection pressure and shear force tests Water content and moisture absorption evaluation Diffusion and transdermal performance evaluation Microbial limit tests Sterility checks Heavy metal residue analysis Organic solvent residue Stability studies Active ingredient quantification Biocompatibility assessments In vivo/in vitro evaluations
End-to-End Service Solutions for Aesthetic Medicine Development
BOC Sciences offers a one-stop formulation development service for medical aesthetics, biotechnology, and high-end cosmetics industries, covering raw material selection, formulation development, GMP manufacturing, and quality control testing. We aim to empower our clients with differentiated, high-performance, and market-oriented product solutions, applicable to diverse scenarios including clinical treatments, skincare, and anti-aging aesthetics.
Medical Aesthetic Product Development
We provide custom development services for injectable formulations (e.g., botulinum toxin, hyaluronic acid, PDRN), including formulation design, sustained-release system construction, biocompatibility assessments, and GMP-level production, helping companies launch innovative high-end injectable aesthetic products that meet skin repair, tightening, and anti-aging treatment needs.
Functional Cosmetics
BOC Sciences supports the development of high-end functional cosmetics in areas such as whitening, antioxidant, and anti-wrinkle, offering stability enhancement and permeation-promoting system design for functional ingredients such as peptides, exosomes, and active oligonucleotides, helping brands create technologically advanced, market-recognized flagship product lines.
Biopharmaceutical Research and Development
We assist biotechnology companies in developing biopolymer-based formulations (e.g., collagen, PCL, PLA, CaHA) widely used in skin fillers, tissue regeneration, and wound healing, providing integrated technical services ranging from material modification and particle size control to in vivo release behavior evaluation.
Minimally Invasive Medical Brands
For clinical applications in minimally invasive aesthetics, we offer custom formulation optimization services for injectable materials and fillers such as PMMA microspheres, PCL sustained-release microparticles, and agarose carrier systems, focusing on improving material injectability, biological stability, and treatment safety, supporting institutions in expanding diverse treatment options.
Skincare Product Contract Manufacturing
BOC Sciences collaborates with multiple international OEM/ODM manufacturers to assist them in developing high-activity, structurally stable skincare ingredients and formulations in areas such as anti-aging, moisturizing repair, and soothing sensitivity. We support the entire process from raw material traceability and formulation ratios to product stability testing.
Medical Research
We offer sample preparation services for medical research institutions, particularly for the development and quality control analysis of cutting-edge ingredients like peptides, exosomes, and PN. We support efficacy validation experiments and the stability, microbial limit, and ingredient content testing of early clinical samples.
Regenerative Medicine Platform
For skin regeneration and tissue engineering, we provide composite carrier system development services, such as multi-nucleotides and CaHA combined systems and peptide-hydroxyapatite co-loaded systems, significantly improving treatment efficiency and meeting cutting-edge medical applications like wound repair and epidermal renewal.
International Registration and Submission Support
BOC Sciences is familiar with the regulatory standards for cosmetics and medical devices across major global markets, including the U.S., Europe, and Asia. We provide essential document support, including ingredient analysis reports, stability studies, microbial testing, GMP production records, assisting clients in completing FDA, EMA, and NMPA international compliance registrations and product submission processes.