Exosome Quality Control Testing
BOC Sciences offers specialized exosome quality control testing services designed to ensure the safety, purity, and functionality of exosome-based products. Using state-of-the-art analytical techniques, we evaluate critical parameters such as particle size distribution, concentration, purity, and biological activity. Our expert team provides accurate and reliable results, assisting clients in the biopharmaceutical and medical research sectors to enhance the safety and efficacy of their exosome products for a variety of therapeutic applications.
Advantages of Cutting-Edge Exosome Quality Control Testing Services
Advanced Detection Equipment
Equipped with high-precision instruments like NTA, flow cytometry, TEM, and DLS to accurately measure exosome size, concentration, morphology, and surface markers.
Professional Technical Team
Experienced researchers and quality control experts proficient in exosome extraction, purification, characterization, and functional validation, ensuring accurate results and expert consultations.
Robust Quality Management
A well-established quality control system ensures consistent and reproducible testing processes that deliver reliable and authoritative results.
Rich Industry Experience
Extensive expertise in exosome research and application, allowing for quick identification and resolution of issues during testing, ensuring efficient and high-quality service.
Comprehensive Testing Services
Offering a broad range of tests for exosome properties such as size, concentration, charge, surface proteins, biological activity, and safety, catering to various client needs.
Fast Turnaround Time
Streamlined testing procedures for increased efficiency, enabling rapid completion of complex exosome quality control tests, saving clients time and costs.
Data Security and Confidentiality
Stringent measures for data management and confidentiality to ensure the safety and privacy of client samples and results, with no unauthorized disclosure.
Continuous Technological Innovation
Constantly integrating the latest advancements in exosome research and testing methods to enhance the quality and capability of our services, providing customers with cutting-edge support.
Reliable Exosome Quality Control Testing Services by BOC Sciences
BOC Sciences offers comprehensive quality control testing services for exosomes, supporting the full spectrum of development and application needs in research and product innovation. Leveraging advanced instrumentation and expert analytical capabilities, we ensure precise characterization of exosome quality attributes, including physicochemical properties, purity, safety, and stability, enabling clients to meet rigorous quality expectations.
Particle Size Distribution
We use NTA and DLS techniques to accurately measure exosome size distribution, ensuring batch-to-batch consistency and supporting downstream processing, formulation optimization, and delivery system development.
Concentration Determination
Exosome concentration is quantified via NTA and protein-based assays to ensure dosing accuracy, maintain product consistency, and support reproducibility in research, therapeutic, or diagnostic applications.
Morphology Characterization
TEM and SEM imaging provide high-resolution visualization of exosome morphology, enabling assessment of shape, membrane structure, and integrity to confirm proper isolation and preservation of vesicular architecture.
Protein Analysis
We apply Western blot, ELISA, and mass spectrometry to identify and quantify key surface and internal proteins, ensuring exosome identity, functional relevance, and purity for research and product development.
Nucleic Acid Analysis
qPCR and NGS platforms enable the detection and quantification of exosomal RNA/DNA cargo, supporting genetic profiling, biomarker discovery, and therapeutic evaluation across various biological and medical models.
Purity Analysis
Purity is assessed using ultracentrifugation, size-exclusion chromatography, and fluorescence labeling to identify contaminants, confirm exosome enrichment, and validate sample quality before downstream application.
Sterility Testing
Sterility testing is performed via microbial culture techniques to confirm the absence of viable bacteria or fungi in exosome preparations, ensuring biological safety and compliance with application requirements.
Endotoxin Detection
Using the LAL assay, we detect and quantify endotoxin contamination in exosome samples, reducing the risk of unwanted immune responses and ensuring product safety for biological use.
Thermal Stability Testing
Thermal stability studies evaluate exosome integrity and cargo retention after exposure to temperature stress, supporting storage condition optimization and formulation robustness under varying environments.
Long-Term Stability Testing
We conduct extended stability testing under controlled storage conditions to monitor changes in exosome structure, concentration, and bioactivity, ensuring product reliability throughout its intended shelf life.
Zeta Potential Analysis
Zeta potential analysis determines the surface charge of exosomes, providing insights into colloidal stability, aggregation tendencies, and formulation behavior critical for product development and delivery efficiency.
Proteomics Profiling
Comprehensive LC-MS/MS-based proteomics reveals the full protein composition of exosomes, enabling functional analysis, mechanism studies, and discovery of diagnostic or therapeutic protein biomarkers.
Exosome Product Categories Supported by BOC Sciences
BOC Sciences provides comprehensive exosome quality testing services tailored to various product categories, including skincare formulations, injectables, topical dressings, and over-the-counter (OTC) beauty products. Each application demands specific analytical strategies to ensure biological activity, formulation stability, and product safety. Our customized testing solutions support both R&D and manufacturing phases, helping clients ensure consistency, efficacy, and quality across a diverse product portfolio.
Exosome Raw Materials
We perform rigorous characterization of exosome raw materials—including vesicle identity, purity, concentration, and surface markers—to ensure consistency, biological activity, and suitability for downstream formulation and therapeutic use.
Exosome Injectables
Our testing includes sterility, endotoxin levels, particle size, and functional assays for injectable exosome products used in anti-aging, scar repair, and dermal regeneration, ensuring high purity and safety for transdermal applications.
Exosome Topical Dressings
We analyze hydrogel- or biomaterial-based dressings for exosome stability, sustained release behavior, and bioactivity retention, supporting their use in wound healing, skin repair, and post-treatment care.
Exosome-Based Beauty Products
We provide comprehensive testing for exosome-enriched beauty products, including moisturizers, serums, and lotions. Our analysis covers protein content, vesicle integrity, purity, and microbiological safety to ensure product quality and skin-enhancing performance.
BOC Sciences' Comprehensive Exosome Quality Control Testing Platform
BOC Sciences has developed a comprehensive, highly integrated exosome quality control testing platform dedicated to providing full-process testing and quality assessment for exosome-based products. This platform combines cutting-edge instrumentation, rigorous testing protocols, and robust data management systems to ensure that every critical aspect of exosome quality, from extraction and purification to final product evaluation, is thoroughly assessed. The platform incorporates advanced instruments designed for precise measurement and analysis of exosome properties, including particle size, concentration, morphology, surface markers, biological activity, and safety. With our extensive experience and a team of skilled professionals, BOC Sciences ensures high-throughput, high-sensitivity, and high-precision testing capabilities, making it suitable for a range of applications in biomedical, pharmaceutical, and research industries.
Nano Particle Tracking Analysis (NTA)
Dynamic Light Scattering (DLS)
Resistive Pulse Sensing (RPS)
Transmission Electron Microscopy (TEM)
Scanning Electron Microscopy (SEM)
Flow Cytometry
Western Blot
ELISA
Ultracentrifuge
Ultrafiltration System
Ultrasonic Processor
Cell Culture Equipment
Fluorescence Microscopy
Real-Time PCR (qPCR)
Sterility Testing Equipment
Endotoxin Testing Equipment
What Aesthetic Applications Does Exosome Quality Control Support?
Exosomes have emerged as a transformative tool in aesthetic medicine, driven by their regenerative, anti-inflammatory, and signaling capabilities. Quality control testing plays a critical role in ensuring the safety, consistency, and efficacy of exosome-based aesthetic products. Below are key aesthetic applications enhanced through rigorous exosome quality assessment:
Skin Repair and Regeneration
Exosomes promote dermal repair by delivering growth factors and signaling molecules that accelerate wound healing and reduce scarring. Quality control ensures functional purity and potency, maximizing therapeutic outcomes in regenerative treatments.
Anti-Aging Treatments
By stimulating collagen production and cellular renewal, exosomes help reduce the appearance of fine lines and wrinkles. Testing for active component stability ensures reliable performance in anti-aging formulations.
Pigmentation Modulation
Exosome formulations can downregulate melanin synthesis pathways, such as the MITF signaling cascade, effectively addressing hyperpigmentation. Quality control ensures consistent expression of key molecules to enhance brightening and tone-evening effects.
Follicle Stimulation
Exosomes are used to support hair regeneration by delivering growth factors to hair follicles and activating dermal papilla cells. Purity and concentration verification are essential to achieving effective follicular response and minimizing variability.
Photoaging Recovery
Exosomes aid in reversing UV-induced skin damage by delivering antioxidants and repair factors to photodamaged skin. Testing ensures these agents retain their bioactivity under medical or cosmetic use conditions.
Cell Signaling Optimization
By facilitating intercellular communication via proteins, RNAs, and lipids, exosomes modulate skin inflammation, repair, and immunity. Comprehensive quality testing safeguards the integrity and bioactivity of these signaling molecules.
Personalized Skincare Formulation
Quality testing enables the customization of exosome formulations tailored to specific skin types and aesthetic goals, supporting the development of precision cosmetic solutions with improved user outcomes.
Product Performance Assurance
Batch-to-batch quality control of particle size, cargo composition, and functional biomarkers ensures the reliability and reproducibility of exosome-based treatments in aesthetic applications.
FAQs
How to test for exosomes?
Exosomes are typically tested using methods such as nanoparticle tracking analysis (NTA) for size and concentration, Western blot or ELISA for surface markers like CD63 and CD81, and functional assays to confirm biological activity. These tests ensure that the exosomes used in aesthetic products are pure, potent, and consistent for applications like skin rejuvenation or anti-aging.
Why is exosome quality control important in aesthetic medicine?
Quality control is essential in aesthetic medicine to ensure the safety, consistency, and efficacy of exosome-based treatments. Proper testing eliminates contaminants, verifies the presence of key active molecules, and confirms functional bioactivity, critical for achieving reliable outcomes in skin repair, pigmentation correction, and anti-aging therapies.
What are the key indicators of a high-quality exosome cosmetic product?
A high-quality exosome product should have a uniform particle size (30–150 nm), high purity with minimal impurities, verified surface markers such as CD63 or CD81, and demonstrated biological activity in regenerative or anti-inflammatory assays, ensuring it delivers visible and consistent aesthetic results.
Can exosome potency be tested before cosmetic use?
Yes, potency can be verified through cell-based assays that evaluate effects on fibroblast proliferation, collagen synthesis, or skin regeneration. These tests confirm that the exosomes retain functional activity and are suitable for medical or cosmetic use in skin rejuvenation, brightening, or anti-wrinkle treatments.
How do you ensure consistency in exosome-based skin treatments?
Consistency is maintained by applying standardized isolation and purification methods, along with rigorous quality testing for each production batch. This includes evaluating size distribution, protein expression, and biological activity, ensuring reliable performance and reproducible results in medical or cosmetic skincare use.