Polynucleotide (PN) Services
BOC Sciences provides high-quality polynucleotide preparation and formulation services along with development and testing solutions designed to satisfy the requirements of multiple industries. Our solutions deliver complete services from small R&D to full-scale production while manufacturing products that meet both cosmetic and pharmaceutical standards according to rigorous GMP regulations. BOC Sciences not only focuses on the extraction, formulation development, and manufacturing of polynucleotides but also provides innovative technical support and precise quality control services, helping industry partners gain a competitive advantage in a constantly changing market environment.
What is Polynucleotide?
Salmon polynucleotides (PN) are DNA fragments extracted from the reproductive cells of salmon, characterized by large molecules, long-chain double helices, and a three-dimensional structural scaffold. They closely resemble human DNA and have excellent biocompatibility. PN has remarkable efficacy, promoting the regeneration of collagen, non-collagen proteins, and elastin, improving fine lines, sagging, and enlarged pores, and enhancing skin elasticity. Its three-dimensional structure also helps water molecules cluster, locking in moisture, balancing sebum production, improving skin texture, and brightening skin tone. Additionally, PN can release PDRN in a sustained manner, exerting anti-inflammatory and soothing effects, and repairing the skin barrier. In terms of applications, PN is widely used in the medical aesthetics field, such as injection fillers, to improve skin density and firmness, increase the thickness of the epidermis and dermis, smooth the skin, and enhance elasticity. It is also used for treating acne scars, dark circles, and other skin concerns.
Advantages of BOC Sciences in Polynucleotide Services
Small to Large-Scale Manufacturing Capabilities
We offer flexible production services ranging from small-batch experimental production to large-scale commercial manufacturing, meeting customer needs at different stages.
Cosmetic and Injectable-Grade Raw Material Supply
We provide industry-standard cosmetic-grade and injectable-grade raw materials to ensure product safety and efficacy across various applications.
GMP-Certified Production Facilities
Our production facilities are GMP-certified, ensuring that each batch meets global quality standards, and supporting customer requirements during clinical and commercial stages.
Comprehensive Quality Control
Through a rigorous quality testing system, covering every step from raw material procurement to product shipment, we ensure the purity, stability, and bioactivity of the products.
Flexible Customization Services
We offer personalized customization services, including formulation development, dosage form design, and process optimization for PNs according to specific customer needs.
Cross-Industry Application Experience
With extensive experience in cosmetics and medical aesthetics, we provide complete solutions from R&D to production, catering to various market demands.
Strict Production and Storage Condition Control
We strictly control temperature, humidity, and other environmental factors during production and storage to ensure stable product quality unaffected by external conditions.
Rapid Response and Flexible Delivery
We can quickly respond to customer needs and provide flexible delivery timelines and services to ensure smooth progress in R&D, clinical, and commercial stages.
Polynucleotide Development Services Offered by BOC Sciences
With years of R&D experience and leading technology, BOC Sciences offers comprehensive PN development services, aiming to help clients achieve full development from raw material extraction to final product. Our services cover various stages, including polynucleotide extraction, formulation optimization, product design, and large-scale production, with a focus on delivering high-quality products that meet specific requirements. Through close collaboration with clients, our R&D team can deeply understand the unique needs of each project and provide customized solutions to ensure the broad applications of polynucleotide products in fields such as pharmaceuticals, vaccine development, and medical aesthetics.
Polynucleotide Preparation Services
BOC Sciences offers professional PN preparation services, covering all steps from salmon genome extraction to the purification process, ensuring high-quality PN products that meet customer research and production needs.
Polynucleotide Formulation Development
We provide formulation development services for PNs, optimizing stability, solubility, and bioactivity by incorporating different excipients and carriers to achieve the best therapeutic effect.
Polynucleotide Gel Development
For local applications of PN products, BOC Sciences offers PN gel development services, ensuring long-term release and effective absorption on the skin or mucous membranes.
Polynucleotides Injectable Development
We also offer injectable PN development services, optimizing injection performance and biocompatibility to meet clinical treatment needs, particularly in medical aesthetics.
GMP Scale Manufacturing Capability of Polynucleotides
BOC Sciences has a robust GMP-scale manufacturing capability for PN, offering production services from small-scale to large-scale, meeting the diverse needs of different customers. Our manufacturing facilities are strictly GMP certified, ensuring that all products meet high-quality standards, fulfilling the requirements of the global market. We provide small-batch production to support preclinical research and early development stages, while also offering large-scale production capabilities to ensure stable and efficient production services during commercialization. Whether for cosmetic-grade or injectable-grade raw materials, BOC Sciences is able to provide PN products that comply with the relevant standards. Cosmetic-grade materials are used for applications such as skin repair and anti-aging, while injectable-grade materials are suitable for stricter medical fields, including immunotherapy and gene therapy. Through precise quality control and stringent production processes, we ensure that each batch of products maintains consistency, safety, and efficacy, meeting customer needs in various application fields.
Polynucleotide Quality Testing Services by BOC Sciences
BOC Sciences provides comprehensive PN quality testing services aimed at ensuring the purity, stability, and bioactivity of every batch of products. With advanced laboratory facilities and an experienced quality control team, we conduct strict testing on polynucleotide products to meet global industry standards. Our quality testing services cover all stages, from raw material receipt to finished product shipment, ensuring that products maintain high quality and efficacy during production, transport, and storage. Whether for clinical research, commercial production, or specialized applications, BOC Sciences can provide reliable and precise testing results, offering comprehensive quality assurance for our clients. Our quality testing services include the following two major testing categories:
Polynucleotide Quality Control Testing
Purity analysis Molecular weight analysis Sequence verification Stability testing Solubility testing Buffer compatibility testing Viscosity testing Sterility testing Endotoxin testing Antioxidant testing
Polynucleotide In Vitro and In Vivo Testing
In vitro immune activation testing Cytotoxicity testing Cell proliferation and differentiation testing Efficacy evaluation Immunogenicity testing In vivo pharmacokinetics studies Tissue distribution analysis Animal immune therapy effectiveness evaluation Long-term safety evaluation Biocompatibility testing
Applications of Polynucleotides in Skincare and Medical Aesthetics
PN have been widely applied in the cosmetics and medical aesthetics fields due to their unique effects in promoting cell repair, anti-aging, and enhancing skin barrier function. With advancements in technology and increasing consumer demand for high-performance skincare products, PN has gradually become an important ingredient in innovative skincare formulations. Its significant effects in improving skin health, delaying aging, and repairing damaged skin have made it widely used in various skincare products. The following are specific applications of PN in cosmetics and medical aesthetics:
Facial Injection Liquids
PN is used in facial injection liquids to deeply nourish the skin, promote collagen generation, slow down the formation of wrinkles and fine lines, and achieve a firming effect, improving facial contours.
Anti-Aging Serums
PN, as a key component in anti-aging serums, promotes skin cell regeneration, improves skin elasticity, reduces signs of aging, and delays the aging process.
Deep Repair Masks
In deep repair masks, PN helps repair damaged skin, provides strong hydration, and promotes the skin's self-repair function, improving skin texture and making it smoother and finer.
Whitening Serums
PN helps renew the stratum corneum, removes dull skin cells, and restores the skin's natural brightness, improving uneven skin tone for a brighter and more radiant complexion.
Skin Repair Lotions
In skin repair lotions, PN enhances the skin barrier function, promotes cell regeneration, and effectively improves skin barrier damage, helping to repair damaged skin areas.
Anti-Wrinkle and Anti-Aging Eye Creams
PN stimulates collagen synthesis in the eye area, reducing fine lines and wrinkles, improving under-eye bags and dark circles, and enhancing the firmness of the skin around the eyes.
Regenerative Repair Injections
As a core ingredient in regenerative repair injections, PN effectively stimulates skin cell self-repair, promotes wound healing, and is used in skin regeneration treatments to repair damaged skin tissues.
Hydrating and Moisturizing Sprays
PN in hydrating sprays provides excellent moisturizing effects, quickly replenishing skin moisture, enhancing hydration, and alleviating dryness-related skin issues, keeping the skin hydrated and smooth for an extended period.
FAQs
Are polynucleotides filler?
Polynucleotides (PN) are not traditional fillers. They are primarily used for skin repair, anti-aging, and promoting cell regeneration, often serving as active ingredients in medical aesthetics products. Unlike fillers, PN improve skin quality by promoting collagen synthesis and enhancing the skin barrier function, rather than simply occupying space or providing instant physical filler effects.
Are polynucleotides safe?
Polynucleotides (PN), after strict quality control and compliance testing, are generally considered safe. Their application in medical aesthetics has a history of use, and they have undergone repeated skin irritation and toxicity tests, which show that PN does not cause significant side effects to the skin or the body when used at appropriate concentrations and conditions. However, individuals with allergies should exercise caution.
How are polynucleotides formed?
Polynucleotides (PN) are long-chain molecules made by linking multiple nucleotide monomers through phosphodiester bonds. Nucleotides consist of a five-carbon sugar, a phosphate group, and a nitrogenous base. In nature, PN are primarily formed during the synthesis of nucleic acids such as DNA and RNA. They can also be artificially synthesized in the laboratory through chemical synthesis or biotechnological methods.
How do polynucleotides work?
Polynucleotides (PN) interact with receptors and enzymes inside cells through their nucleotide sequences, promoting cell repair and regeneration. In skincare, PN enhance collagen synthesis, improve skin barrier function, and stimulate cellular metabolism, leading to anti-aging, repair of damaged skin, and improved skin elasticity. Additionally, PN have antioxidant properties that help combat damage caused by free radicals.