Polydeoxyribonucleotide (PDRN) Services

Polydeoxyribonucleotide (PDRN) Services

Within modern biomedicine and aesthetic medicine research areas, polydeoxyribonucleotide (PDRN) has achieved substantial attention because of its distinctive biological activity and extensive application possibilities. BOC Sciences utilizes its leading-edge technological platform and comprehensive research experience along with tailored services to deliver top-notch PDRN preparation and development solutions. We provide complete solutions that speed up product commercialization for both small laboratory research and large production endeavors. BOC Sciences achieves product quality consistency through ongoing technological and process optimization while meeting specific requirements, which promotes global application of PDRN technology.

What is Hyaluronic Acid?

What is PDRN?

Polydeoxyribonucleotide (PDRN) consists of deoxyribonucleotide polymers usually extracted from fish testis or other cellular materials. This substance demonstrates biological activity by supporting cell repair processes while providing anti-inflammatory benefits and metabolic enhancement, which enables its extensive use in aesthetic medicine treatments, skincare applications, and wound recovery procedures. PDRN formulation possibilities include injectable solutions, gels, and microspheres, which function to improve skin appearance while slowing aging and promoting faster tissue repair and regeneration. The demand for skincare and anti-aging products has grown in recent years, which has positioned PDRN as a naturally derived, effective component at the center of biomedical research and clinical applications.

Advantages of BOC Sciences in PDRN Development

Advanced Technological Platform

Leveraging cutting-edge technology, BOC Sciences provides efficient PDRN preparation and development solutions.

Customized Services

Tailored PDRN product development and manufacturing services to meet the diverse needs of different application fields.

Stringent Quality Control

Each batch of PDRN undergoes rigorous quality testing to ensure product consistency and stability.

Diverse Application Fields

PDRN finds extensive applications in skincare, aesthetic medicine, and wound healing, meeting the diverse demands of the market.

Highly Experienced R&D Team

A team of seasoned researchers provides professional technical support and customized solutions for clients.

Comprehensive Product Line

From raw material preparation to formulation development, BOC Sciences offers a complete range of PDRN products to fulfill various needs.

Large-Scale Production Capability

With scalable manufacturing capacity, we ensure high-quality production while meeting market demands.

Global Service Network

Providing efficient and professional services to global clients, helping them succeed in international markets.

PDRN Development Services by BOC Sciences

BOC Sciences offers comprehensive PDRN preparation services, including but not limited to PDRN raw material synthesis and formulation development. Our team employs advanced technologies and processes to ensure high purity and biological activity of PDRN products. Our raw material preparation services allow for precise synthesis of desired PDRN fragments tailored to client requirements, ensuring optimal biological activity through optimized processing methods. In addition to raw material preparation, we offer various PDRN formulations, including injectables, gels, and nanoparticles, to meet diverse application needs.

High Molecular Weight HA

PDRN Raw Material Preparation

During PDRN raw material preparation, BOC Sciences utilizes advanced synthesis techniques to accurately extract and fragment various PDRN sequences based on client specifications.

Medium Molecular Weight HA

PDRN Formulation Services

In addition to raw material preparation, BOC Sciences provides custom formulation services for a variety of PDRN-based products, including emulsions, serums, injectables, eye drops, gels, and dressings.

Low Molecular Weight HA

PDRN Injection Development

BOC Sciences provides comprehensive PDRN injectable development services, covering all aspects from formulation design to manufacturing, ensuring product safety, stability, and bioactivity.

Oligomeric HA

PDRN Filler Development

BOC Sciences offers professional PDRN filler development services, incorporating PDRN as a bioactive component into traditional fillers to promote skin cell regeneration and repair.

Oligomeric HA

PDRN Gel Development

We specialize in PDRN gel formulation, focusing on optimizing composition, enhancing stability, and evaluating efficacy to ensure uniform coverage on the skin surface.

Oligomeric HA

PDRN Nanoparticle Development

Our team develops PDRN nanoparticles with specific particle sizes, loading efficiency, and controlled release rates to meet various clinical and cosmetic application requirements.

Oligomeric HA

PDRN Microsphere Development

Our team focuses on microsphere preparation techniques, particle size control, and drug release characteristics, offering customized PDRN microspheres with controlled release profiles and biodegradable properties based on client needs.

Get a Quote

Advanced GMP Large-Scale Manufacturing of PDRN

BOC Sciences possesses advanced large-scale PDRN manufacturing capabilities to meet the global demand for high-quality PDRN products. Our manufacturing facilities strictly adhere to cGMP standards, featuring a sterile production environment and a comprehensive quality control system to guarantee the safety and efficacy of PDRN in pharmaceuticals, skincare, and biomaterials. Leveraging cutting-edge biotechnological processes, we provide a fully optimized workflow from laboratory-scale trials to pilot-scale expansion and industrial-scale production, ensuring efficient conversion from raw materials to final products. Our production sites are equipped with high-capacity bioreactors, advanced chromatographic purification systems, and automated filling equipment, supporting PDRN manufacturing from kilogram to ton-scale to meet the bulk order needs of global clients. BOC Sciences also offers customized production services, allowing flexible adjustments to PDRN molecular weight, concentration, and formulation to meet the specific technical requirements of various applications.

PDRN Quality Testing Services by BOC Sciences

To ensure the quality compliance of PDRN products at all stages, BOC Sciences provides comprehensive quality testing services, covering various aspects such as purity, stability, and bioactivity assessment of PDRN. We employ cutting-edge testing technologies in accordance with international standards to ensure that every step meets stringent quality control requirements. From raw material preparation and formulation development to production processes and final product quality control, BOC Sciences offers a wide range of tests, including meticulous physicochemical testing, as well as cellular and animal experiments, to guarantee the safety, efficacy, and consistency of PDRN products, meeting the high standards required by clients across different fields.

PDRN Quality Control Testing

PDRN Purity Analysis Molecular Weight Distribution Analysis Degradation Rate Testing pH Value and Solubility Testing Heavy Metal Detection Endotoxin Testing Microbial Limit Testing Thermal Stability Testing Appearance and Color Consistency Testing

PDRN In Vitro and In Vivo Testing

Cell Proliferation and Migration Testing Collagen Synthesis Testing Cytotoxicity Evaluation Skin Penetration Testing Inflammatory Response Assessment Pharmacodynamic Evaluation in Animal Models Biodistribution Studies Pharmacokinetics Analysis Immunogenicity Testing

Applications of PDRN in Skincare and Medical Aesthetics

With continuous advancements in biomedical technology, PDRN has demonstrated extensive application potential in various fields due to its remarkable tissue repair and cellular regeneration capabilities. Leveraging advanced synthesis techniques and manufacturing expertise, BOC Sciences provides high-quality PDRN products for research institutions, pharmaceutical companies, and biotechnology enterprises, facilitating innovation in skin repair, anti-aging, biomedical materials, tissue engineering, and drug development. Our PDRN products feature high purity, excellent biocompatibility, and customizable formulations, making them widely applicable in medical dressings, biomaterials, cell therapy, regenerative medicine, skincare, and anti-inflammatory repair.

Medical Face Mask Ingredient

PDRN can be incorporated into medical-grade face masks as a highly effective repair component, promoting skin cell regeneration and accelerating wound healing or post-surgical skin recovery.

Medical Gel Ingredient

In medical gels, PDRN plays a key role in promoting tissue repair and is widely used for wound care, post-surgical healing, and soothing sensitive skin.

Anti-Aging Serum Component

As a crucial ingredient in anti-aging skincare products, PDRN promotes skin cell renewal and accelerates the synthesis of collagen and elastin, thereby enhancing skin elasticity and improving the appearance of fine lines, wrinkles, and sagging.

Post-Light Therapy Repair Agent

With outstanding anti-inflammatory and tissue repair properties, PDRN is used in post-light therapy repair products, such as those designed for recovery after laser treatments, intense pulsed light (IPL), and radiofrequency procedures.

Chronic Wound Healing

In the treatment of chronic wounds, including diabetic foot ulcers, pressure sores, and surgical wounds, PDRN promotes angiogenesis, enhances cell regeneration, and accelerates wound healing.

Burn Dressing Ingredient

PDRN contributes to skin regeneration in burn treatment, accelerating the healing of burn wounds. It improves microcirculation, reduces the risk of infections, and minimizes scarring by promoting fibroblast proliferation and collagen synthesis.

Ophthalmic Eye Drop Ingredient

PDRN enhances corneal epithelial cell proliferation and repair, alleviates eye inflammation, stabilizes the tear film, and promotes overall eye health, making it a key active ingredient in premium eye drops.

Orthopedic Implant Material

In orthopedic applications, the ability of PDRN to promote angiogenesis and tissue regeneration makes it highly valuable in bone defect filling and cartilage repair, contributing to enhanced patient recovery outcomes.

FAQ

FAQs

What is PDRN used for?

PDRN (Polydeoxyribonucleotide) is widely applied in skin repair, anti-aging, tissue regeneration, and regenerative medicine. It promotes cell proliferation, angiogenesis, and collagen synthesis, making it a valuable ingredient in medical aesthetics (such as anti-aging skincare products and aesthetic injections), chronic wound healing (such as diabetic foot ulcers and burns), orthopedic treatments, and ophthalmology. PDRN also effectively reduces inflammation, enhances the skin barrier, and improves skin elasticity, establishing itself as an essential active component in biomedical and skincare products.

PDRN is not directly equivalent to salmon sperm but is extracted from the sperm or reproductive cells of salmon or other salmonid species. Through advanced enzymatic hydrolysis technology, these DNA fragments are degraded into appropriately sized PDRN molecules for applications in skin repair, anti-aging, and regenerative medicine. PDRN is highly biocompatible and safe, undergoing rigorous purification processes to eliminate allergenic proteins, making it suitable for various medical and aesthetic applications.

PRP (Platelet-Rich Plasma) and PDRN (Polydeoxyribonucleotide) are both bioactive substances used for skin repair and tissue regeneration, but they differ in source and mechanism of action. PRP is extracted from the patient's own blood and contains abundant growth factors that stimulate cell growth and repair. PDRN, on the other hand, is derived from salmon DNA and primarily promotes cell regeneration, tissue repair, and improved microcirculation. Compared to PRP, PDRN is more stable, can be produced under standardized conditions, and does not rely on individual blood quality, making it suitable for broader medical and aesthetic applications.

Both PN (Polynucleotide) and PDRN (Polydeoxyribonucleotide) promote tissue repair and anti-aging, but they differ in molecular structure and function. PN consists of larger nucleotide polymers, providing prolonged stimulation for collagen synthesis and skin barrier repair. PDRN, on the other hand, primarily facilitates cell regeneration and angiogenesis through DNA metabolism pathways. The choice between PN and PDRN depends on specific application needs—PN is better suited for long-term repair, while PDRN is ideal for rapid healing and tissue regeneration.