Exosome Services
BOC Sciences provides full-spectrum exosome services tailored to the needs of biomedical and aesthetic research. Our offerings include exosome isolation, purification, surface modification, characterization, and bio-functional evaluation. We support various applications such as regenerative medicine, targeted drug delivery, and advanced skincare formulations. Leveraging robust analytical platforms and scientific expertise, we ensure precision, consistency, and scalability, delivering customized solutions that accelerate discovery and product innovation across medical and cosmetic domains.
Key Strengths of BOC Sciences' Exosome Services
Proprietary Technology Platform
BOC Sciences operates an advanced exosome technology platform that integrates isolation, purification, characterization, and functional enhancement, supporting diverse applications in cosmetic and biomedical research.
Rigorous Quality Standards
Our multi-parameter quality control system includes assessments of exosome purity, particle size distribution, and biomarker expression, ensuring consistent performance across batches.
High Consistency and Stability
Standardized manufacturing processes and automated controls enable batch-to-batch consistency and long-term storage stability, ideal for sustained use in R&D workflows.
Diverse Cell Source Portfolio
We offer exosomes derived from mesenchymal stem cells, adipose-derived stem cells, and plant cells, giving clients flexible options tailored to their specific application needs.
Differentiated Functional Profiles
Through engineering and enrichment technologies, we provide exosomes with targeted bioactivities such as anti-inflammatory, regenerative, or reparative properties for precise research objectives.
Experienced Multidisciplinary Team
Our team of experts spans cell biology, molecular science, and dermatological research, offering insightful technical consultation and hands-on support throughout the service lifecycle.
End-to-End Service Framework
From project design and sample sourcing to process development, analytics, and scale-up, our integrated service model ensures efficient project execution and seamless transitions between stages.
Process Optimization and Scale-Up Capability
With robust process development expertise, we support smooth scale-up from laboratory to pilot-scale production, facilitating the transition from research to advanced development phases.
Comprehensive Exosome Services by BOC Sciences
BOC Sciences offers a comprehensive suite of exosome services designed to meet the needs of biomedical, aesthetic, and therapeutic research. From preparation and formulation to rigorous quality control and validation, we provide fully customized solutions to support your research and development goals.
Exosome Preparation Services
We offer high-quality exosome isolation and purification from various biological sources, including stem cells, plasma, and cell cultures. Our advanced purification techniques ensure high yields and purity, making our exosome preparations ideal for a wide range of applications in regenerative medicine, drug delivery, and diagnostics.
Exosome Formulation Services
Our exosome formulation services focus on optimizing exosome stability, delivery, and bioactivity for specific applications. We customize formulations to suit the needs of your research, including targeting, encapsulation, and cryopreservation, ensuring that exosomes maintain their integrity and functionality during storage and delivery.
Exosome Quality Control Testing
We conduct comprehensive quality control tests to ensure the purity, integrity, and functionality of exosomes. Our testing includes particle size distribution analysis, purity verification, functional assays, and safety evaluations, all designed to meet the highest industry standards and ensure reliable, reproducible results for your applications.
Exosome In Vitro and In Vivo Studies
BOC Sciences provides in vitro and in vivo validation studies to assess the biological activity, toxicity, and therapeutic potential of exosomes. Our services include cell viability assays, immunomodulatory testing, pharmacokinetics studies, and animal model testing to help translate exosome research into practical therapeutic solutions.
Cutting-edge Exosome Technologies to Support Diverse Research Needs
BOC Sciences employs a suite of advanced and validated technologies to extract, purify, and refine exosomes from a broad range of biological sources. Our methods are designed to ensure high yield, structural integrity, and functional preservation of extracellular vesicles, supporting stringent research and product development demands.
Differential Ultracentrifugation
A widely adopted and scalable approach, differential ultracentrifugation leverages high-speed centrifugation and density gradient layering to separate exosomes from cells, debris, and protein contaminants. This technique offers efficient particle isolation while maintaining vesicle integrity, making it suitable for processing large sample volumes with reproducible outcomes.
Immunoaffinity-Based Capture
BOC Sciences applies immunoaffinity separation using monoclonal antibodies targeting canonical exosomal surface markers such as CD9, CD63, and CD81. This high specific method enables the isolation of defined exosome subpopulations with minimal contamination, supporting precise molecular profiling and targeted downstream applications.
Nanoparticle-Assisted Isolation
We integrate nanoparticle-based separation strategies, including magnetic bead conjugation and nanostructured filtration platforms, to achieve gentle and efficient exosome purification. These techniques reduce shear forces and sample degradation, allowing for high-throughput processing while preserving bioactivity.
Size-Exclusion Chromatography
Size-exclusion chromatography (SEC) is employed to separate exosomes from proteins and other small particles based on hydrodynamic volume. This non-destructive and highly reproducible method ensures high purity without compromising exosomal morphology or function.
Microfiltration and Ultrafiltration
Membrane-based concentration techniques such as tangential flow filtration (TFF) and ultrafiltration are used for scalable volume reduction and size-based fractionation. These processes enable efficient pre-purification and buffer exchange with minimal product loss and are suitable for both upstream and downstream workflows.
Process Optimization and Characterization
Our exosome preparation workflows are supported by rigorous in-process analytics, including nanoparticle tracking analysis (NTA), dynamic light scattering (DLS), and transmission electron microscopy (TEM), ensuring batch-to-batch consistency and structural fidelity throughout the entire purification pipeline.
GMP-Compliant Exosome Solutions by BOC Sciences
BOC Sciences offers exosome services that meet GMP standards, ensuring the highest levels of quality and safety for both cosmetic and medical applications. Our state-of-the-art production facilities for exosome isolation, characterization, and formulation are designed to comply with stringent GMP guidelines. This guarantees that every step, from cell sourcing, exosome extraction, purification, functionalization, to final packaging, is carried out with minimal contamination risks. Our comprehensive quality control system continuously monitors all stages, ensuring purity, functionality, and reproducibility. Furthermore, our scalable production capabilities allow for flexible batch sizes, catering to both research and large-scale commercial needs while maintaining consistency and performance across all products.
Comprehensive Exosome Quality Control and Evaluation Services by BOC Sciences
BOC Sciences provides an extensive range of exosome quality control and application testing services to ensure optimal consistency, safety, and performance for biomedical and therapeutic purposes. With cutting-edge technologies and a skilled team of experts, we conduct rigorous testing at every stage of production—from raw material sourcing to final product release. Additionally, our in vitro and in vivo studies support the effective translation of exosome-based solutions for both research and medical applications.
Exosome Quality Control Testing
Purity Analysis
Integrity Assessment
Functional Testing
Batch Consistency Testing
Microbial Contamination Detection
Genomics and Proteomics Analysis
Safety Evaluation
Exosome In Vitro and In Vivo Studies
Cell Function Testing
Bioactivity Assessment
Cytotoxicity Testing
Immunomodulatory Testing
Animal Model Studies
Pharmacokinetics Studies
Pharmacodynamics Evaluation
Safety Assessment
What Applications Do Exosomes Support in Aesthetic Fields?
Exosomes are nanoscale vesicles secreted by cells, known for their role in intercellular communication and delivery of bioactive molecules. With their inherent regenerative and modulatory capabilities, exosomes have emerged as valuable tools in aesthetic and medical research, supporting applications ranging from skin rejuvenation to inflammatory disease treatment and personalized therapeutics.
Skin Regeneration
Exosomes promote collagen and elastin synthesis by delivering growth factors and cytokines, accelerating wound healing and improving skin elasticity. They are used in post-burn recovery and postoperative skin regeneration, enhancing overall skin quality.
Photoaging Prevention
Rich in antioxidants and anti-inflammatory agents, exosomes help reduce wrinkles and fine lines, delay aging signs, and boost skin hydration and elasticity, contributing to a more youthful and radiant appearance.
Scar Repair and Prevention
Exosomes support angiogenesis and modulate inflammation, expediting scar healing and minimizing scar formation. They are commonly applied in acne scar treatment, surgical scar management, and skin injury recovery.
Hair Regeneration
Stem cell-derived exosomes stimulate follicle activity and improve the scalp microenvironment, effectively promoting hair growth and addressing androgenic alopecia, such as alopecia areata.
Skincare Product Integration
Exosomes are increasingly incorporated into creams, serums, and masks to enhance hydration, reinforce the skin barrier, and delay visible aging. These formulations typically use plant- or stem cell-derived exosomes.
Microneedling Therapy Enhancement
Exosomes are used alongside microneedling, laser, or phototherapy treatments to support faster skin regeneration and improve therapeutic outcomes by stimulating local cell repair.
Inflammatory Skin Diseases
Exosomes show promise in treating psoriasis, rosacea, and other inflammatory skin conditions by modulating immune responses and reducing skin inflammation, aiding in skin barrier restoration.
Personalized Medicine
As natural biomarkers, exosomes enable early disease detection and monitoring through molecular analysis of their contents (e.g., miRNA). This application supports precision medicine, especially in skin cancer and neurodegenerative disease management.
FAQs
What is an exosome used for?
Exosomes are widely used in biomedical and research fields due to their ability to mediate intercellular communication. They facilitate tissue regeneration, modulate immune responses, and promote wound healing. Exosomes are valuable tools for drug delivery, diagnostics, and the development of personalized medicine, as they can carry bioactive molecules such as proteins, lipids, and RNA.
Are exosomes better than PRP?
Exosomes and platelet-rich plasma (PRP) both promote tissue regeneration, but they differ in composition and efficacy. Exosomes deliver highly concentrated signaling molecules with defined therapeutic actions, offering superior anti-inflammatory, regenerative, and anti-aging effects. Unlike PRP, which relies on the patient's platelets, exosomes are cell-free and standardized, allowing for more consistent outcomes.
What is the function of the exosomes?
Exosomes serve as biological messengers that transport proteins, lipids, and nucleic acids between cells. Their primary function is to regulate intercellular communication and influence cellular behavior, such as proliferation, differentiation, and immune modulation. In therapeutic contexts, exosomes promote tissue repair, suppress inflammation, and facilitate regeneration by delivering specific molecular signals to target cells, making them critical in both natural healing and engineered treatments.
What are exosomes in skincare?
In skincare, exosomes are bioactive vesicles used to enhance skin regeneration, hydration, and anti-aging effects. Derived from plant cells, stem cells, or cultured human cells, they are incorporated into serums, creams, and masks to deliver growth factors, peptides, and antioxidants directly to skin cells. Exosome-enriched formulations help reduce fine lines, improve elasticity, boost collagen production, and restore the skin barrier, resulting in smoother, healthier, and more youthful-looking skin.