PDRN In Vitro and In Vivo Testing
BOC Sciences delivers complete in vitro and in vivo testing solutions for polydeoxyribonucleotide (PDRN) to help its development and quality control throughout multiple applications. Our testing platform evaluates every stage of production from raw materials to completed formulations, which includes PDRN raw materials and other forms such as injectables and gels, to deliver precise testing results for our clients. Our advanced laboratory facilities combined with extensive technical expertise enable us to effectively assess the biological activity, safety, and stability of PDRN across multiple biological systems while meeting international standards.
What is Polydeoxyribonucleotide?
PDRN is a polynucleotide polymer synthesized from deoxyribonucleotides through enzymatic cleavage, with significant biological activity. PDRN exerts its unique biological effects by promoting tissue repair and regeneration. It can stimulate cell proliferation, accelerate wound healing, and possesses anti-inflammatory and antioxidant properties, making it widely used in skin repair, wound healing, and anti-aging fields. In the field of medical aesthetics, PDRN is commonly used as an effective skin repair factor for facial fillers, skin regeneration, and cell repair. Additionally, PDRN has shown potential applications in orthopedics, cardiovascular treatments, and more. Due to its properties of promoting neovascularization and enhancing cell regeneration, PDRN provides a non-surgical treatment option for patients, becoming a key component in medical aesthetics and anti-aging treatments.
Advantages of BOC Sciences in PDRN Testing
Advanced Testing Platform
BOC Sciences is equipped with advanced in vitro and in vivo testing platforms, ensuring the accuracy and efficiency of tests.
Professional Technical Team
Our research team has many years of experience in biologic product testing, providing comprehensive and professional technical support.
Customized Services
We offer personalized testing plans based on client needs to ensure each PDRN test meets specific research goals.
Comprehensive Animal Models
We offer various animal models, including mice, rats, and large animals, to meet different testing needs and ensure the reliability of experimental data.
Precise Analytical Equipment
BOC Sciences possesses first-class analytical and testing equipment, including HPLC, mass spectrometry, NMR, and more, ensuring precise testing results.
Efficient Report Generation
We provide fast data reports and customize analysis according to client requirements, ensuring clear and understandable data.
Rich Industry Experience
BOC Sciences has accumulated extensive experience in biologic product testing, providing professional solutions for diverse clients.
Global Service Network
We offer services to clients worldwide, ensuring high-quality PDRN testing support no matter where you are.
In Vitro Testing Services for PDRN by BOC Sciences
BOC Sciences provides a series of advanced in vitro testing services to evaluate the biological activity and safety of PDRN. Our in vitro tests cover areas such as cell culture, cytotoxicity testing, cell proliferation and migration experiments, and gene expression analysis. These tests help study the effects of PDRN on different cell types, such as skin cells, fibroblasts, and endothelial cells. In evaluating cell proliferation and repair ability, we use techniques such as MTT and flow cytometry to ensure the biological activity of PDRN is accurately assessed. Additionally, we provide quantitative analysis of PDRN's anti-inflammatory, antioxidant, and immune-modulatory functions, supporting its efficacy in clinical applications.
Cell Proliferation Detection
Using methods such as MTT and CCK-8, we assess the proliferative effects of PDRN on different cell types (e.g., skin cells, fibroblasts) to understand its potential in cell growth and repair.
Cell Migration Experiment
Through scratch assays and Transwell experiments, we investigate PDRN's impact on cell migration, especially its role in wound healing and regeneration, simulating PDRN's mechanism of promoting tissue repair.
Cytotoxicity Testing
We use techniques like MTT and LDH release assays to evaluate the toxicity of PDRN on different cell lines, ensuring its safety for clinical applications and avoiding potential side effects.
Anti-inflammatory Evaluation
By measuring cytokine levels (such as TNF-α, IL-6), we evaluate PDRN's inhibitory effects on inflammation and explore its potential for anti-inflammatory treatment, especially for skin diseases or post-trauma applications.
Antioxidant Capability Testing
Through free radical scavenging assays and DPPH testing, we study PDRN's inhibitory effects on oxidative stress, assessing its potential as an antioxidant in aging and skin protection.
Gene Expression Analysis
Using real-time quantitative PCR (qPCR), we analyze PDRN's regulatory effects on various key genes (e.g., growth factors, cell cycle regulatory genes), further understanding its molecular mechanisms in cell repair and regeneration.
Immune Regulation Evaluation
Through flow cytometry and ELISA, we analyze PDRN's effects on immune cells, exploring its applications in immune regulation, anti-allergy, and immune repair.
Multilayered Biological Analysis
We combine various detection techniques, such as Western blot and ELISA, to study the mechanisms of PDRN in different cell types, providing comprehensive biological effect analysis to ensure its performance in complex biological systems.
In Vivo Testing Services for PDRN by BOC Sciences
In the field of in vivo testing, BOC Sciences has a powerful animal model platform that allows for comprehensive evaluation of PDRN's effects in vivo. Our In vivo testing services include animal model construction, pharmacokinetics, toxicity evaluation, and efficacy assessment. By using animal models such as mice and rats, we investigate PDRN's effects on tissue repair, anti-inflammation, angiogenesis, and more. Our services also include a comprehensive evaluation of different PDRN formulations (e.g., injectables, gels) in vivo to ensure the product's biological activity and safety. All in vivo tests strictly follow ethical guidelines to ensure scientific validity and regulatory compliance in animal experiments.
Pharmacokinetics Evaluation
We analyze plasma, tissue, and urine samples after administration to study the absorption, distribution, metabolism, and excretion of PDRN in animals, helping clients understand its pharmacokinetic characteristics.
Pharmacodynamics Evaluation
By applying PDRN formulations in animal models, we assess the effects of PDRN on tissue regeneration, wound healing, anti-inflammatory, and repair actions.
Toxicity Evaluation
Through both long-term and short-term toxicity studies, we assess the impact of PDRN on animal health at different doses, avoiding potential side effects or adverse reactions in clinical applications.
Wound Healing Testing
In mouse or rat wound models, we assess PDRN’s promoting effects on wound healing through skin scratch assays and skin wound healing models.
Immune Response Evaluation
Using flow cytometry and ELISA, we analyze the effects of PDRN on the immune system in animals, studying its abilities in immune regulation and anti-inflammatory effects.
Skin Repair Function Testing
We regularly observe the wound healing process and conduct histological analysis to accurately evaluate PDRN's repair effects and skin maintenance potential.
Tissue Distribution Analysis
By sampling and conducting histological examinations of different tissues, we study PDRN's distribution in the body, understanding its accumulation and mode of action in various organs and tissues.
Long-term Effect Monitoring
In long-term administration models, we periodically assess the long-term effects of PDRN, including its impact on animal health and the sustainability of therapeutic effects.
PDRN Product Categories Supported by Our PDRN Testing Services
BOC Sciences offers testing services for PDRN across various product forms, including PDRN raw materials, formulations, injectables, fillers, gels, nanoparticles, and microspheres. Whether for initial raw material testing or final formulation quality control, we provide efficient and professional testing services. The purity and structural analysis of PDRN raw materials, as well as the stability and particle size distribution of formulations, are evaluated under strict standards. Additionally, for specialized forms of PDRN, such as nanoparticles and microspheres, we analyze key parameters like particle size and morphology using techniques such as Dynamic Light Scattering (DLS) and Transmission Electron Microscopy (TEM). All testing services aim to ensure that every batch of PDRN products meets the highest standards of functionality, quality, and safety.
Advanced Animal and Cell Platforms for In Vitro and In Vivo Testing
BOC Sciences' in vitro and in vivo testing relies on advanced animal and cell platforms. We possess an extensive cell library, including various human and animal-derived cell lines, enabling us to conduct a wide range of functional tests, such as cell proliferation, migration, and differentiation. In terms of animal platforms, we use mouse, rat, and rabbit models to simulate different pathological conditions, such as wound repair and inflammation, providing accurate in vivo data for PDRN research. Furthermore, we have a substantial immunology testing platform for analyzing immune responses, further evaluating PDRN's immunomodulatory effects.
Cell Platforms
Fibroblast Cell Lines Keratinocyte Cell Lines Endothelial Cell Lines Immune Cell Lines Nerve Cell Lines Adipocyte Cell Lines
Animal Platforms
Mouse Models Rat Models Rabbit Models Pig Models Dog Models Monkey Models
Advanced Analytical Testing Platforms for In Vitro and In Vivo Testing
BOC Sciences provides world-class advanced analytical testing platforms that support precise analyses for in vitro and in vivo testing. Our analytical platforms integrate cutting-edge equipment and technologies that efficiently and accurately assess the biological effects and pharmacokinetic characteristics of PDRN and other bioproducts. Whether for drug screening, toxicity testing, cell biology research, or monitoring in vivo effects in animals, our testing platforms offer high sensitivity and low error results, ensuring reliable and scientific data. By continually upgrading our testing equipment, we meet the diverse needs of clients across various industries, especially in PDRN-related research, providing strong data support for every stage of scientific research and product development.
High-Performance Liquid Chromatography (HPLC) Mass Spectrometry (MS) Nuclear Magnetic Resonance (NMR) Fluorescence Spectrometer Flow Cytometer Real-Time Quantitative PCR (qPCR) Western Blot Analyzer Cell Counter UHPLC-MS ELISA Reader Automated Small Animal Imaging System Scanning Electron Microscope (SEM)
Applications of PDRN in Skincare and Medical Aesthetics
In the skincare and medical aesthetics fields, PDRN has become a popular therapeutic ingredient due to its skin-repairing, anti-aging, and regenerative properties. PDRN stimulates skin cell regeneration, enhances collagen synthesis, and improves skin elasticity and firmness. As a natural repair factor, PDRN is used in anti-aging treatments to alleviate skin laxity, fine lines, and wrinkles, promoting skin tissue repair and renewal. Additionally, PDRN is used in medical aesthetics for facial fillers, injectables, and localized treatments, commonly applied in scar repair and post-surgical recovery, offering a non-surgical cosmetic treatment option. Through ongoing research and clinical application, PDRN has shown significant potential in skincare and medical aesthetics.
Medical Mask Ingredients
PDRN is a key ingredient in medical masks, effectively promoting skin cell regeneration, repairing damaged skin, improving skin elasticity and radiance, and reducing fine lines and wrinkles.
Medical Gel Ingredients
Used in medical gel products for skin wounds, burns, and post-surgical repairs, PDRN accelerates skin healing, reduces scarring, and maintains smooth and polished skin.
Hydrating Injection Ingredients
As a primary component of hydrating injections, PDRN nourishes the skin deeply, enhancing skin hydration, improving dryness, roughness, and fine lines, and restoring elasticity and firmness.
Cosmetics Ingredients
PDRN can be used as a restorative component in cosmetics, mitigating the skin damage caused by prolonged makeup use, relieving dryness and irritation, and keeping the skin moisturized and smooth.
Eye Drops Ingredients
PDRN is used in eye drops, offering moisturizing and reparative effects, helping relieve eye dryness, fatigue, and redness, and promoting cell repair and regeneration in the eye area.
Health Supplement Ingredients
As an ingredient in health supplements, PDRN helps improve skin health, enhances skin resistance, slows down aging processes, and maintains smooth and firm skin.
Skincare Serum Ingredients
In skincare serums, PDRN accelerates skin cell metabolism, enhances repair capabilities, reduces signs of aging such as wrinkles and laxity, and improves overall skin health.
Facial Filler Ingredients
PDRN can be used as a bio-based component in facial fillers, providing long-lasting skin firming effects, restoring facial contours, and enhancing skin fullness and radiance.