Polynucleotide Quality Control Testing
The application of polynucleotides (PN) in medical aesthetics and biomedicine has made product quality and safety key priorities for the industry. BOC Sciences utilizes its advanced analytical technology platform and experienced research team to deliver full-scope quality testing and analysis services for PN products across categories that include PN raw materials and PN gels as well as PN injections and PN formulations. We cover all stages from product development through quality control to market approval, which guarantees product purity, stability, and activity standards that meet global requirements while helping customers advance to clinical or market phases. BOC Sciences builds a globally leading PN analysis platform with efficient and reliable technical support for clients.
What are Polynucleotides?
Polynucleotides (PN) are natural macromolecules formed by the connection of various nucleotides through phosphodiester bonds. In the fields of medical aesthetics and regenerative medicine, salmon-derived PN are widely used due to their superior biological activity and repair properties. Salmon PN is primarily extracted from salmon eggs and contains rich nucleotides, RNA fragments, and their derivatives, exhibiting strong biological activity, especially in cell repair, anti-aging, and regenerative medicine. The main applications of PN in medical aesthetics include promoting skin repair, anti-aging, enhancing skin elasticity, and improving skin barrier function. It accelerates skin cell regeneration and collagen synthesis, slows down the aging process, repairs damaged skin, and demonstrates significant antioxidant effects. Furthermore, PN enhances the skin's self-repair ability, counteracting environmental damage to the skin, and is widely used in anti-aging skincare creams, masks, serums, and other products in the medical aesthetics industry.
Advantages of BOC Sciences in Polynucleotide Analysis
Specialized Team
BOC Sciences has an interdisciplinary team of experts in biochemistry, pharmaceutical analysis, and molecular biology, ensuring professionalism and efficiency in the field of PN analysis.
Full Process Service Support
From PN raw material development to formulation quality control, we provide full-process support from laboratory research to large-scale production, helping clients achieve efficient product development and manufacturing.
Highly Customized Solutions
We tailor exclusive PN analysis methods and testing plans based on customer needs, ensuring that each test meets specific product quality standards and industry requirements.
Advanced Testing Technologies
BOC Sciences has introduced globally leading testing instruments and technologies, such as LC-MS/MS, HPLC, GPC, etc., ensuring high accuracy, sensitivity, and reproducibility of test results.
Rapid Response and Delivery
We provide efficient project management, ensuring that each project is delivered on time. Whether in early-stage development or production, fast testing cycles help clients accelerate product market entry.
Strict Quality Control
All PN testing adheres to international pharmacopoeia standards, ensuring that every analysis meets high-quality requirements and safeguards product competitiveness and compliance in the market.
International Standards and Compliance
BOC Sciences' testing services meet certification requirements from global regulatory bodies such as the US FDA, supporting product registration and promotion in international markets.
Strong Data Support and Reporting
We provide detailed and standardized data reports to help clients clearly understand analysis results, further optimize product quality and processes, and support scientific research and clinical studies.
Polynucleotide Quality Testing Services by BOC Sciences
BOC Sciences offers comprehensive and accurate PN quality testing services to ensure the purity, stability, safety, and compliance of PN products. Our quality testing covers all aspects from PN raw materials to final formulations, helping clients meet various quality requirements and ensuring consistency throughout the product lifecycle. In addition to routine tests, we can also develop customized testing plans according to specific customer needs. Whether for raw material control, formulation development, production batch release, or market regulatory requirements, we provide the most professional support to ensure product quality and compliance.
Purity Analysis and Impurity Monitoring
Using high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) technology, we precisely measure PN purity and identify impurities, ensuring the absence of harmful components and guaranteeing product quality and safety.
Molecular Weight and Distribution Detection
Through gel permeation chromatography (GPC) technology, we accurately determine the molecular weight and distribution of PN, assessing its biological activity and providing data support for product efficacy and safety.
Content Measurement
Using UV-Vis spectrophotometry and fluorescence methods, we precisely determine the content of PN components, ensuring that active ingredients meet standards, particularly for injection products.
Endotoxin and Microbial Limit Testing
We offer endotoxin testing (such as the LAL method) and microbial limit testing to ensure that PN products meet clinical application requirements, free of endotoxins and microbial contamination.
Degradation Products and Stability Analysis
We conduct detailed analysis of PN degradation products and evaluate their stability under different storage conditions to ensure that long-term stored products remain effective and safe during use.
pH, Osmolality, and Viscosity Testing
Using pH meters, osmometry, and rotary viscometers, we test the physicochemical properties of PN formulations to optimize the formulation and ensure comfort and biocompatibility during injection.
Residual Solvent and Impurity Analysis
Using gas chromatography (GC), we detect residual solvents and impurities in PN to ensure that the product meets pharmacopoeia standards, especially for cosmetic or injectable PN products.
Stability and Shelf Life Testing
Through accelerated stability tests and long-term stability tests, we evaluate the shelf life of PN products, ensuring that they maintain optimal efficacy and safety within the designated expiration period.
Polynucleotide Product Categories Supported by BOC Sciences
BOC Sciences offers a wide range of PN product testing services, covering quality control and analysis of PN in different forms. These tests support quality assurance of PN raw materials and various PN formulations and final products, ensuring that every step from R&D to production meets the highest standards. We use advanced instruments and standardized operating procedures to ensure efficient analysis and precise testing of all types of PN products, providing reliable data support to help clients optimize product quality and accelerate market promotion.
PN Raw Materials
We offer comprehensive quality testing services for PN raw materials, including purity, molecular weight, and impurity analysis, ensuring that the raw materials meet manufacturing standards and are suitable for subsequent production and formulation.
PN Formulations
For PN formulations (such as topical formulations), we provide complete testing services to ensure that the PN content, stability, uniformity of active ingredients, and performance in different formulations meet quality requirements.
PN Gels
For PN gel products used in pharmaceuticals and cosmetics, we provide testing for rheology, pH, stability, degradation products, and component content, ensuring that the gel performs well during use.
PN Injectables
As a high-precision product, PN injections require strict quality control. We offer sterility testing, endotoxin testing, osmolality, pH, stability, and other essential parameter tests to ensure their safety and effectiveness.
Customized Polynucleotide Analysis Method Development Services
BOC Sciences offers customized PN analysis method development services, designed to meet the specific needs of different clients. By combining advanced technology platforms and extensive experience, we provide clients with tailored, efficient, and accurate analysis methods. Whether for new product development, optimization of existing products, or specific research needs, our team can deliver personalized solutions. Our analysis method development services cover various aspects, from PN purity analysis and content determination to stability testing. We are committed to providing high-sensitivity, high-precision testing solutions using multiple techniques such as HPLC and UV-Vis. In addition, BOC Sciences' analysis method development services extend beyond routine testing to support specific requirements in fields like medical aesthetics and regenerative medicine, ensuring the quality and safety of PN products in diverse applications. With our profound expertise and leading technology, BOC Sciences helps clients efficiently complete product development and quality control tasks, facilitating the smooth market entry of innovative products.
Comprehensive Quality Control Platform from BOC Sciences
BOC Sciences has established a multidimensional, full-process PN quality analysis platform, covering all aspects of testing from molecular structure analysis to process impurity detection. The platform is equipped with advanced analytical instruments and automated operating systems, following international standards to achieve high throughput, high sensitivity, and high accuracy. Specifically, to address the diversity of PN products, we have built a database of testing methods with strong specificity and high reproducibility, capable of handling complex sample matrices, detecting low-concentration components, and tracking trace impurities. Whether it's small sample analysis during the R&D stage or quality release in bulk production, BOC Sciences' testing platform provides robust support for clients.
High-performance liquid chromatograph (HPLC) Gas chromatograph (GC) Capillary electrophoresis (CE) Mass spectrometer (LC-MS/MS) Gel permeation chromatograph (GPC) Ultraviolet-visible spectrophotometer (UV-Vis) Fluorescence spectrophotometer Infrared spectrometer (FTIR) Automated endotoxin detector (LAL test) pH/osmotic pressure testing instruments Rotary viscometer Microbial limit testing system
Applications of Polynucleotide in Cosmetics and Medical Aesthetics
PN have gained significant attention in the fields of skincare and medical aesthetics in recent years, particularly for their excellent effects on anti-aging, skin repair, and tissue regeneration. Due to their natural origin and strong biological activity, salmon-extracted polynucleotides have become a key ingredient in many high-end skincare and medical aesthetics products. BOC Sciences' PN testing services broadly support research and applications across various fields, particularly in the skincare and medical aesthetics industries. Our high-quality testing services provide critical data support for various research directions, helping drive the development and application of PN products.
Medical Aesthetic Product Development
Our testing services aid the medical aesthetics industry in anti-aging, skin repair, and cell regeneration, evaluating PN's skin absorption, antioxidant, and biocompatibility for better formulations.
Injectable Solutions and Formulation Research
PN testing services ensure injectable solutions' stability, sterility, and regulatory compliance through stability studies and preclinical testing, supporting the development and optimization of formulations.
Skin Repair and Regeneration
We assess PN's effectiveness in promoting wound healing, improving skin elasticity, and enhancing barrier function, ensuring stability and activity in skin repair and regenerative products.
Promoting Wound Healing
PN accelerates wound healing by reducing inflammation and enhancing skin barrier function, aiding recovery after surgery or treatments, and minimizing scarring risks.
Repair Masks
Polynucleotides are commonly used in repair-type masks, especially for sensitive skin or skin that has been damaged. They accelerate cell repair, reduce inflammation, and enhance the skin's barrier function.
Anti-Aging Serums
Polynucleotides are widely used in anti-aging serums. They promote skin cell regeneration and increase collagen synthesis, helping to reduce fine lines and wrinkles.
Moisturizing Lotions
The moisturizing effects of polynucleotides make them an important ingredient in highly effective moisturizing lotions. They help strengthen the skin's moisture barrier, providing long-lasting hydration, especially for dry or dehydrated skin.
Eye Injection Solutions
Polynucleotide injections stimulate collagen synthesis, enhancing the elasticity and firmness of the skin around the eyes. This helps reduce the appearance of wrinkles and fine lines, restoring the youthful look of the eye area.